A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome

AIMS: Transient outward potassium current (I(to)) is thought to be central to the pathogenesis of the Brugada syndrome (BrS). However, an I((to)) activator has not been available with which to validate this hypothesis. Here, we provide a direct test of the hypothesis using a novel I(to) activator, N...

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Détails bibliographiques
Auteurs principaux: Calloe, Kirstine, Cordeiro, Jonathan M., Di Diego, José M., Hansen, Rie S., Grunnet, Morten, Olesen, Søren Peter, Antzelevitch, Charles
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2009
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Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642600/
https://ncbi.nlm.nih.gov/pubmed/19073629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvn339
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