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A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome

AIMS: Transient outward potassium current (I(to)) is thought to be central to the pathogenesis of the Brugada syndrome (BrS). However, an I((to)) activator has not been available with which to validate this hypothesis. Here, we provide a direct test of the hypothesis using a novel I(to) activator, N...

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Detalhes bibliográficos
Main Authors: Calloe, Kirstine, Cordeiro, Jonathan M., Di Diego, José M., Hansen, Rie S., Grunnet, Morten, Olesen, Søren Peter, Antzelevitch, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642600/
https://ncbi.nlm.nih.gov/pubmed/19073629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvn339
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