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Recombinant scrapie-like prion protein of 106 amino acids is soluble

The N terminus of the scrapie isoform of prion protein (PrP(Sc)) can be truncated without loss of scrapie infectivity and, correspondingly, the truncation of the N terminus of the cellular isoform, PrP(C), still permits conversion into PrP(Sc). To assess whether additional segments of the PrP molecu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Muramoto, Tamaki, Scott, Michael, Cohen, Fred E., Prusiner, Stanley B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1996
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26426/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8986833/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.26.15457
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