Protein Kinase A Anchoring via AKAP150 Is Essential for TRPV1 Modulation by Forskolin and Prostaglandin E(2) in Mouse Sensory Neurons

Phosphorylation-dependent modulation of the vanilloid receptor TRPV1 is one of the key mechanisms mediating the hyperalgesic effects of inflammatory mediators, such as prostaglandin E(2) (PGE(2)). However, little is known about the molecular organization of the TRPV1 phosphorylation complex and spec...

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Autori principali: Schnizler, Katrin, Shutov, Leonid P., Van Kanegan, Michael J., Merrill, Michelle A., Nichols, Blake, McKnight, G. Stanley, Strack, Stefan, Hell, Johannes W., Usachev, Yuriy M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2641040/
https://ncbi.nlm.nih.gov/pubmed/18463244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0233-08.2008
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