Protein Kinase A Anchoring via AKAP150 Is Essential for TRPV1 Modulation by Forskolin and Prostaglandin E(2) in Mouse Sensory Neurons

Phosphorylation-dependent modulation of the vanilloid receptor TRPV1 is one of the key mechanisms mediating the hyperalgesic effects of inflammatory mediators, such as prostaglandin E(2) (PGE(2)). However, little is known about the molecular organization of the TRPV1 phosphorylation complex and spec...

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Autors principals: Schnizler, Katrin, Shutov, Leonid P., Van Kanegan, Michael J., Merrill, Michelle A., Nichols, Blake, McKnight, G. Stanley, Strack, Stefan, Hell, Johannes W., Usachev, Yuriy M.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2641040/
https://ncbi.nlm.nih.gov/pubmed/18463244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0233-08.2008
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