A Kinase Anchor Protein 150 (AKAP150)-associated Protein Kinase A Limits Dendritic Spine Density

The A kinase anchor protein AKAP150 recruits the cAMP-dependent protein kinase (PKA) to dendritic spines. Here we show that in AKAP150 (AKAP5) knock-out (KO) mice frequency of miniature excitatory post-synaptic currents (mEPSC) and inhibitory post-synaptic currents (mIPSC) are elevated at 2 weeks an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lu, Yuan, Zha, Xiang-ming, Kim, Eun Young, Schachtele, Scott, Dailey, Michael E., Hall, Duane D., Strack, Stefan, Green, Steven H., Hoffman, Dax A., Hell, Johannes W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2011
Pynciau:
Neurobiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143614/
https://ncbi.nlm.nih.gov/pubmed/21652711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254912
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