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A genotype-phenotype examination of Cyclin D1 on risk and outcome of squamous cell carcinoma of the head and neck

PURPOSE: The variant allele of CCND1 G870A encodes a splice variant of the Cyclin D1 protein which possesses an increased half-life. To confirm the phenotypic effect of the variant allele, we examined the immunohistochemical staining pattern of the protein in tumors from a case population of head an...

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Detalhes bibliográficos
Main Authors: Marsit, Carmen J., Black, Candice C., Posner, Marshall R., Kelsey, Karl T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640470/
https://ncbi.nlm.nih.gov/pubmed/18413827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4368
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