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Hypermethylation of E-Cadherin Is an Independent Predictor of Improved Survival in Head and Neck Squamous Cell Carcinoma
BACKGROUND: The loss of E-cadherin (ECAD) protein expression has been linked to aggressive head and neck squamous cell carcinoma (HNSCC). Promoter hypermethylation of the cadherin 1, type 1 (CDH1) gene (encoding ECAD) is 1 mechanism by which this protein can be inactivated, although this epigenetic...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3645304/ https://ncbi.nlm.nih.gov/pubmed/18711702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.23770 |
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