Transfection activity of layer-by-layer plasmid DNA/poly(ethylenimine) films deposited on PLGA microparticles

Layer-by-layer (LbL) assemblies of DNA and polycations on the surface of colloidal templates can be used for gene delivery. Plasmid DNA encoding for secreted alkaline phosphatase (SEAP) was used to deposit LbL films with poly(ethylenimine) (PEI) on the surface of polystyrene and poly(lactide-co-glyc...

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Autori principali: Kakade, Sandeep, Manickam, Devika Soundara, Handa, Hitesh, Mao, Guangzhao, Oupický, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640435/
https://ncbi.nlm.nih.gov/pubmed/18786622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2008.08.019
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