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Reducible poly(amido ethylenimine)-based gene delivery system for improved nucleus trafficking of plasmid DNA

In a non-viral gene delivery system, localization of a plasmid DNA in the nucleus is a prerequisite for expression of a desired therapeutic protein encoded in the plasmid DNA. In this study, a reducible polymer-based gene delivery system for improved intracellular trafficking and nuclear translocati...

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Bibliographic Details
Main Authors: Jeong, Ji Hoon, Kim, Sun Hwa, Christensen, Lane V., Feijen, Jan, Kim, Sung Wan
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828932/
https://ncbi.nlm.nih.gov/pubmed/20078099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc9003525
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