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Effect of cell membrane thiols and reduction-triggered disassembly on transfection activity of bioreducible polyplexes

Bioreducible polyplexes are promising vectors for delivery of nucleic acids due to low toxicity and favorable transfection activity. The often improved transfection is usually explained by enhanced intracellular reductive disassembly of the polyplexes. This study evaluated the effect of enhanced red...

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Bibliografiske detaljer
Main Authors: Li, Jing, Manickam, Devika S., Chen, Jun, Oupicky, David
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730823/
https://ncbi.nlm.nih.gov/pubmed/22406090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2012.02.020
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