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DNA Release Dynamics from Reducible Polyplexes by AFM

Controlled intracellular disassembly of polyelectrolyte complexes of polycations and DNA (polyplexes) is a crucial step for the success of non-viral gene delivery. Motivated by our previous observation of different gene delivery performance among multiblock reducible copolypeptide vectors [Bioconjug...

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Detalhes bibliográficos
Main Authors: Wan, Lei, Manickam, Devika S., Oupický, David, Mao, Guangzhao
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825055/
https://ncbi.nlm.nih.gov/pubmed/18839970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la802088y
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