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Reducible poly(2-dimethylaminoethyl methacrylate): Synthesis, cytotoxicity, and gene delivery activity

Reducible polycations represent promising carriers of therapeutic nucleic acids. Oligomers of 2-dimethylaminoethyl methacrylate (DMAEMA) containing terminal thiol groups were synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization using difunctional chain transfer agent...

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Detalhes bibliográficos
Main Authors: You, Ye-Zi, Manickam, Devika Soundara, Zhou, Qing-Hui, Oupický, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063492/
https://ncbi.nlm.nih.gov/pubmed/17574292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2007.04.020
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