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Decreased Perivascular Fibrosis but Not Cardiac Hypertrophy in ROCK1(+/−) Haploinsufficient Mice

BACKGROUND: Rho GTPase and its downstream target, Rho-associated kinase (ROCK), have been implicated in diverse cardiovascular diseases such as cardiac hypertrophy. However, pharmacological inhibitors of ROCK are not entirely specific, nor can they discriminate between the ROCK isoforms ROCK1 and RO...

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מידע ביבליוגרפי
Main Authors: Rikitake, Yoshiyuki, Oyama, Naotsugu, Wang, Chao-Yung C., Noma, Kensuke, Satoh, Minoru, Kim, Hyung-Hwan, Liao, James K.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640100/
https://ncbi.nlm.nih.gov/pubmed/16260635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.105.584623
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