ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury

Although Rho-associated kinase (ROCK) activity has been implicated in cardiovascular diseases, the tissue- and isoform-specific roles of ROCKs in the vascular response to injury are not known. To address the role of ROCKs in this process, we generated haploinsufficient Rock1 (Rock1(+/–)) and Rock2 (...

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Detalhes bibliográficos
Main Authors: Noma, Kensuke, Rikitake, Yoshiyuki, Oyama, Naotsugu, Yan, Guijun, Alcaide, Pilar, Liu, Ping-Yen, Wang, Hongwei, Ahl, Daniela, Sawada, Naoki, Okamoto, Ryuji, Hiroi, Yukio, Shimizu, Koichi, Luscinskas, Francis W., Sun, Jianxin, Liao, James K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293333/
https://ncbi.nlm.nih.gov/pubmed/18414683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29226
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