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Deficiency of ROCK1 in bone marrow-derived cells protects against atherosclerosis in LDLR(−/−) mice

Rho kinases (ROCKs) are serine-threonine protein kinases that regulate the actin cytoskeleton. Recent studies suggest that ROCKs also play an important role in cardiovascular disease. However, the isoform- and tissue-specific role of ROCKs in mediating this process is unknown. Using homologous recom...

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Detalhes bibliográficos
Main Authors: Wang, Hong-Wei, Liu, Ping-Yen, Oyama, Naotsugu, Rikitake, Yoshiyuki, Kitamoto, Shiro, Gitlin, Jonathan, Liao, James K., Boisvert, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2537434/
https://ncbi.nlm.nih.gov/pubmed/18556458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-108829
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