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ROCKs as therapeutic targets in cardiovascular diseases

There is growing evidence that Rho-kinases (ROCKs), the immediate downstream targets of the small guanosine triphosphate-binding protein Rho, may contribute to cardiovascular disease. ROCKs play a central role in diverse cellular functions such as smooth muscle contraction, stress fiber formation an...

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Detalhes bibliográficos
Main Authors: Rikitake, Yoshiyuki, Liao, James K
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643373/
https://ncbi.nlm.nih.gov/pubmed/15889972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14779072.3.3.441
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