FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2

The Rho-associated coiled-coil containing kinases, ROCK1 and ROCK2, are important regulators of cell shape, migration, and proliferation through effects on the actin cytoskeleton. However, it is not known whether ROCK2 plays an important role in the development of cardiac hypertrophy. To determine w...

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Detalhes bibliográficos
Main Authors: Okamoto, Ryuji, Li, Yuxin, Noma, Kensuke, Hiroi, Yukio, Liu, Ping-Yen, Taniguchi, Masaya, Ito, Masaaki, Liao, James K.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606529/
https://ncbi.nlm.nih.gov/pubmed/23271052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-217018
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