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Chimeric NKG2D receptor-expressing T cells as an immunotherapy for multiple myeloma
OBJECTIVE: Most myeloma tumor cells from patients express NKG2D ligands. We have reported the development of a chimeric NKG2D receptor (chNKG2D), which consists of the NKG2D receptor fused to the CD3ζ chain. T cells expressing this receptor kill and produce cytokines in response to NKG2D-ligand+ tum...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2638591/ https://ncbi.nlm.nih.gov/pubmed/18599182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2008.04.010 |
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