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Hepatocyte Growth Factor and Sonic Hedgehog Expression in Cerebellar Neural Progenitor Cells Costimulate Medulloblastoma Initiation and Growth

Medulloblastomas are malignant brain tumors that arise by transformation of neural progenitor cells in the cerebellum in children. Treatment-related neurotoxicity has created a critical need to identify signaling molecules that can be targeted therapeutically to maximize tumor growth suppression and...

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Hlavní autoři: Binning, Mandy J., Niazi, Toba, Pedone, Carolyn A., Lal, Bachchu, Eberhart, Charles G., Kim, K. Jin, Laterra, John, Fults, Daniel W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638505/
https://ncbi.nlm.nih.gov/pubmed/18829539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1899
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