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Multipoint linkage-disequilibrium mapping narrows location interval and identifies mutation heterogeneity
Single-nucleotide polymorphism (SNP) genotypes were recently examined in an 890-kb region flanking the human gene CYP2D6. Single-marker and haplotype-based analyses identified, with genomewide significance (P < 10(-7)), a 403-kb interval displaying strong linkage disequilibrium (LD) with predicte...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC263833/ https://ncbi.nlm.nih.gov/pubmed/14597696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2235031100 |
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