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Multipoint Linkage-Disequilibrium–Mapping Approach Based on the Case-Parent Trio Design

In the present study we propose a multipoint approach, for the mapping of genes, that is based on the case-parent trio design. We first derive an expression for the expected preferential–allele-transmission statistics for transmission, from either parent to an affected child, for an arbitrary locati...

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Bibliografische gegevens
Hoofdauteurs: Liang, Kung-Yee, Hsu, Fang-Chi, Beaty, Terri H., Barnes, Kathleen C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society of Human Genetics 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1275648/
https://ncbi.nlm.nih.gov/pubmed/11254451
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