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Examining the effect of linkage disequilibrium on multipoint linkage analysis
Most linkage programs assume linkage equilibrium among multiple linked markers. This assumption may lead to bias for tightly linked markers where strong linkage disequilibrium (LD) exists. We used simulated data from Genetic Analysis Workshop 14 to examine the possible effect of LD on multipoint lin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1866697/ https://ncbi.nlm.nih.gov/pubmed/16451698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S83 |
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