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Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice
Elongation of very long chain fatty acids (ELOVL)5 is one of seven mammalian fatty acid condensing enzymes involved in microsomal fatty acid elongation. To determine the in vivo substrates and function of ELOVL5, we generated Elovl5(−/−) mice. Studies using liver microsomal protein from wild-type an...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Biochemistry and Molecular Biology
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2638104/ https://ncbi.nlm.nih.gov/pubmed/18838740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800383-JLR200 |
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