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Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice

Elongation of very long chain fatty acids (ELOVL)5 is one of seven mammalian fatty acid condensing enzymes involved in microsomal fatty acid elongation. To determine the in vivo substrates and function of ELOVL5, we generated Elovl5(−/−) mice. Studies using liver microsomal protein from wild-type an...

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Bibliografiska uppgifter
Huvudupphovsmän: Moon, Young-Ah, Hammer, Robert E., Horton, Jay D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638104/
https://ncbi.nlm.nih.gov/pubmed/18838740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800383-JLR200
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