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Conversion of the 2 Cl(−)/1 H(+) antiporter ClC-5 in a NO(3)(−)/H(+) antiporter by a single point mutation
Several members of the CLC family are secondary active anion/proton exchangers, and not passive chloride channels. Among the exchangers, the endosomal ClC-5 protein that is mutated in Dent's disease shows an extreme outward rectification that precludes a precise determination of its transport s...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637338/ https://ncbi.nlm.nih.gov/pubmed/19131966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.284 |
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