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On the Mechanism of Gating Charge Movement of ClC-5, a Human Cl(−)/H(+) Antiporter
ClC-5 is a Cl(−)/H(+) antiporter that functions in endosomes and is important for endocytosis in the proximal tubule. The mechanism of transport coupling and voltage dependence in ClC-5 is unclear. Recently, a transport-deficient ClC-5 mutant (E268A) was shown to exhibit transient capacitive current...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3341549/ https://ncbi.nlm.nih.gov/pubmed/22824269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.067 |
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