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C5a Receptor Mediates Neutrophil Activation and ANCA-Induced Glomerulonephritis

Anti-neutrophil cytoplasmic autoantibody (ANCA)-induced necrotizing crescentic glomerulonephritis (NCGN) requires complement participation in its pathogenesis. We tested the hypothesis that the anaphylatoxin C5a is pivotal to disease induction via the neutrophil C5a receptor (C5aR). Supernatants fro...

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Bibliografske podrobnosti
Main Authors: Schreiber, Adrian, Xiao, Hong, Jennette, J. Charles, Schneider, Wolfgang, Luft, Friedrich C., Kettritz, Ralph
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637051/
https://ncbi.nlm.nih.gov/pubmed/19073822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008050497
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