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Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice

Shortened telomeres are a normal consequence of cell division. However, telomere shortening past a critical point results in cellular senescence and death. To determine the effect of telomere shortening on lung, four generations of B6.Cg-Terc(tm1Rdp) mice, null for the terc component of telomerase,...

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Bibliografiske detaljer
Main Authors: Lee, Jooeun, Reddy, Raghava, Barsky, Lora, Scholes, Jessica, Chen, Hui, Shi, Wei, Driscoll, Barbara
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636955/
https://ncbi.nlm.nih.gov/pubmed/18952756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90411.2008
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