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Partial pneumonectomy of telomerase null mice carrying shortened telomeres initiates cell growth arrest resulting in a limited compensatory growth response

Telomerase mutations and significantly shortened chromosomal telomeres have recently been implicated in human lung pathologies. Natural telomere shortening is an inevitable consequence of aging, which is also a risk factor for development of lung disease. However, the impact of shortened telomeres a...

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Detalhes bibliográficos
Main Authors: Jackson, Sha-Ron, Lee, Jooeun, Reddy, Raghava, Williams, Genevieve N., Kikuchi, Alexander, Freiberg, Yael, Warburton, David, Driscoll, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119124/
https://ncbi.nlm.nih.gov/pubmed/21460122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00409.2010
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