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Partial pneumonectomy of telomerase null mice carrying shortened telomeres initiates cell growth arrest resulting in a limited compensatory growth response

Telomerase mutations and significantly shortened chromosomal telomeres have recently been implicated in human lung pathologies. Natural telomere shortening is an inevitable consequence of aging, which is also a risk factor for development of lung disease. However, the impact of shortened telomeres a...

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Bibliografiske detaljer
Main Authors: Jackson, Sha-Ron, Lee, Jooeun, Reddy, Raghava, Williams, Genevieve N., Kikuchi, Alexander, Freiberg, Yael, Warburton, David, Driscoll, Barbara
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119124/
https://ncbi.nlm.nih.gov/pubmed/21460122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00409.2010
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