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Characterization of the molecular phenotype of two ARVC-related PKP2 mutations

BACKGROUND: Arrhythmogenic right ventricular cardiomyopathy (ARVC), has been linked to mutations in desmosomal proteins, including plakophilin2 (PKP2). Little is known about the changes in cellular function and structure that follow expression of ARVC-relevant PKP2 mutations. OBJECTIVE: Here, we inv...

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Autors principals: Joshi-Mukherjee, Rosy, Coombs, Wanda, Musa, Hassan, Oxford, Eva, Taffet, Steven, Delmar, Mario
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636742/
https://ncbi.nlm.nih.gov/pubmed/19084810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2008.09.009
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