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Characterization of the molecular phenotype of two ARVC-related PKP2 mutations

BACKGROUND: Arrhythmogenic right ventricular cardiomyopathy (ARVC), has been linked to mutations in desmosomal proteins, including plakophilin2 (PKP2). Little is known about the changes in cellular function and structure that follow expression of ARVC-relevant PKP2 mutations. OBJECTIVE: Here, we inv...

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Main Authors: Joshi-Mukherjee, Rosy, Coombs, Wanda, Musa, Hassan, Oxford, Eva, Taffet, Steven, Delmar, Mario
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636742/
https://ncbi.nlm.nih.gov/pubmed/19084810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2008.09.009
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