Design and characterization of the first peptidomimetic molecule that prevents acidification-induced closure of cardiac gap junctions

BACKGROUND: Gap junctions are potential targets for pharmacological intervention. We have previously developed a series of peptide sequences that prevent closure of Cx43 channels, bind to cardiac Cx43 and prevent acidification-induced uncoupling of cardiac gap junctions. OBJECTIVE: We aimed to ident...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Verma, Vandana, Larsen, Bjarne Due, Coombs, Wanda, Lin, Xianming, Sarrou, Eliana, Taffet, Steven M., Delmar, Mario
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948861/
https://ncbi.nlm.nih.gov/pubmed/20601149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2010.06.028
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker