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Structure of human protein kinase CK2α2 with a potent indazole-derivative inhibitor
Casein kinase 2 (CK2) is a serine/threonine kinase that functions as a heterotetramer composed of two catalytic subunits (CK2α1 or CK2α2) and two regulatory subunits (CK2β). The two isozymes CK2α1 and CK2α2 play distinguishable roles in healthy subjects and in patients with diseases such as cancer,...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
International Union of Crystallography
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2635861/ https://ncbi.nlm.nih.gov/pubmed/19193990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108043194 |
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