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Crystal structures of human CK2α2 in new crystal forms arising from a subtle difference in salt concentration

The catalytic subunits of protein kinase CK2 are classified into two subtypes: CK2α1 and CK2α2. CK2α1 is an attractive drug-discovery target for various diseases such as cancers and nephritis. CK2α2 is defined as an off-target of CK2α1 and is a potential target in the development of male contracepti...

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Bibliografiske detaljer
Udgivet i:Acta Crystallogr F Struct Biol Commun
Main Authors: Tsuyuguchi, Masato, Nakaniwa, Tetsuko, Kinoshita, Takayoshi
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931141/
https://ncbi.nlm.nih.gov/pubmed/29717996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18005204
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