Crystal structure of human CK2α at 1.06 Å resolution

The Ser/Thr kinase CK2 consists of two catalytic subunits (CK2α) and a dimer of the regulatory subunits (CK2β), and is a ubiquitous enzyme that regulates growth, proliferation and the survival of cells. CK2 is a remarkable drug target for potentially treating a wide variety of tumours and glomerulon...

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Bibliografiske detaljer
Main Authors: Kinoshita, Takayoshi, Nakaniwa, Tetsuko, Sekiguchi, Yusuke, Sogabe, Yuri, Sakurai, Atsushi, Nakamura, Shinya, Nakanishi, Isao
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2013
Fag:
Diffraction Structural Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795567/
https://ncbi.nlm.nih.gov/pubmed/24121351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0909049513020785
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