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Expression, purification, crystallization and preliminary X-ray studies of the Ebola VP35 interferon inhibitory domain
Ebola VP35 is a multifunctional protein that is important for host immune suppression and pathogenesis. VP35 contains an N-terminal oligomerization domain and a C-terminal interferon inhibitory domain (IID). Mutations within the VP35 IID result in loss of host immune suppression. Here, efforts to cr...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
International Union of Crystallography
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2635856/ https://ncbi.nlm.nih.gov/pubmed/19194011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108044187 |
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