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HDAC3 as a Molecular Chaperone for Shuttling Phosphorylated TR2 to PML: A Novel Deacetylase Activity-Independent Function of HDAC3

TR2 is an orphan nuclear receptor specifically expressed in early embryos (Wei and Hsu, 1994), and a transcription factor for transcriptional regulation of important genes in stem cells including the gate keeper Oct4 (Park et al. 2007). TR2 is known to function as an activator (Wei et al. 2000), or...

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Detalhes bibliográficos
Main Authors: Gupta, Pawan, Ho, Ping-Chih, Ha, Sung Gil, Lin, Yi-Wei, Wei, Li-Na
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634961/
https://ncbi.nlm.nih.gov/pubmed/19204783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004363
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