Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression

We previously reported an intricate mechanism underlying the homeostasis of Oct4 expression in normally proliferating stem cell culture of P19, mediated by SUMOylation of orphan nuclear receptor TR2. In the present study, we identify a signaling pathway initiated from the nongenomic activity of all-...

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Detalhes bibliográficos
Main Authors: Gupta, Pawan, Ho, Ping-Chih, Huq, MD Mostaqul, Ha, Sung Gil, Park, Sung Wook, Khan, Amjad Ali, Tsai, Nien-Pei, Wei, Li-Na
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516243/
https://ncbi.nlm.nih.gov/pubmed/18682553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710561105
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