Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression

We previously reported an intricate mechanism underlying the homeostasis of Oct4 expression in normally proliferating stem cell culture of P19, mediated by SUMOylation of orphan nuclear receptor TR2. In the present study, we identify a signaling pathway initiated from the nongenomic activity of all-...

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Bibliografiske detaljer
Main Authors: Gupta, Pawan, Ho, Ping-Chih, Huq, MD Mostaqul, Ha, Sung Gil, Park, Sung Wook, Khan, Amjad Ali, Tsai, Nien-Pei, Wei, Li-Na
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516243/
https://ncbi.nlm.nih.gov/pubmed/18682553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710561105
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