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Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli

Bacterial aromatic polyketides are important therapeutic compounds including front line antibiotics and anticancer drugs. It is one of the last remaining major classes of natural products of which the biosynthesis has not been reconstituted in the genetically superior host Escherichia coli. Here, we...

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Autors principals: Zhang, Wenjun, Li, Yanran, Tang, Yi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634872/
https://ncbi.nlm.nih.gov/pubmed/19075227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809084105
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