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Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli

Bacterial aromatic polyketides are important therapeutic compounds including front line antibiotics and anticancer drugs. It is one of the last remaining major classes of natural products of which the biosynthesis has not been reconstituted in the genetically superior host Escherichia coli. Here, we...

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Detalhes bibliográficos
Main Authors: Zhang, Wenjun, Li, Yanran, Tang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634872/
https://ncbi.nlm.nih.gov/pubmed/19075227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809084105
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