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Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli
Bacterial aromatic polyketides are important therapeutic compounds including front line antibiotics and anticancer drugs. It is one of the last remaining major classes of natural products of which the biosynthesis has not been reconstituted in the genetically superior host Escherichia coli. Here, we...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2008
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634872/ https://ncbi.nlm.nih.gov/pubmed/19075227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809084105 |
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