Evidence for penetration of diphtheria toxin to the cytosol through a prelysosomal membrane.
To kill mammalian cells, diphtheria toxin must be endocytosed and encounter a low pH within intracellular vesicles. The low pH initiates penetration of the catalytically active A fragment of the toxin through a membrane and into the cytosol where the A fragment arrests protein synthesis. To investig...
Na minha lista:
| Udgivet i: | Infect Immun |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1984
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC263484/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6706404/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.44.1.145-150.1984 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|