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Competition and collaboration: GATA-3, PU.1, and Notch signaling in early T-cell fate determination

T-cell precursors remain developmentally plastic for multiple cell generations after entering the thymus, preserving access to developmental alternatives of macrophage, dendritic cell, and even mast-cell fates. The underlying regulatory basis of this plasticity is that early T-cell differentiation d...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Rothenberg, Ellen V., Scripture-Adams, Deirdre D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634812/
https://ncbi.nlm.nih.gov/pubmed/18768329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2008.07.006
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