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Architecture of a lymphomyeloid developmental switch controlled by PU.1, Notch and Gata3
Hematopoiesis is a classic system with which to study developmental potentials and to investigate gene regulatory networks that control choices among alternate lineages. T-cell progenitors seeding the thymus retain several lineage potentials. The transcription factor PU.1 is involved in the decision...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Company of Biologists
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3585658/ https://ncbi.nlm.nih.gov/pubmed/23444353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.088559 |
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