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Architecture of a lymphomyeloid developmental switch controlled by PU.1, Notch and Gata3

Hematopoiesis is a classic system with which to study developmental potentials and to investigate gene regulatory networks that control choices among alternate lineages. T-cell progenitors seeding the thymus retain several lineage potentials. The transcription factor PU.1 is involved in the decision...

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Autors principals: Del Real, Marissa Morales, Rothenberg, Ellen V.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585658/
https://ncbi.nlm.nih.gov/pubmed/23444353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.088559
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