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RASSF1A hypermethylation in pretreatment serum DNA of neuroblastoma patients: a prognostic marker

The tumour suppressor gene RASSF1A is known to be frequently silenced by promoter hypermethylation in neuroblastoma tumours. Here we explored the possible prognostic significance of aberrant promoter hypermethylation of RASSF1A in serum DNA samples of patients with neuroblastoma as a surrogate marke...

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Detalhes bibliográficos
Main Authors: Misawa, A, Tanaka, S, Yagyu, S, Tsuchiya, K, Iehara, T, Sugimoto, T, Hosoi, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634715/
https://ncbi.nlm.nih.gov/pubmed/19165202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604887
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