Serum-Based Quantification of MYCN Gene Amplification in Young Patients with Neuroblastoma: Potential Utility as a Surrogate Biomarker for Neuroblastoma

We previously developed a method for determining MYCN gene amplification status using cell-free DNA fragments released from cancer cells into the blood of patients with neuroblastoma (NB). Here, we analyzed the relationship between MYCN amplification (MNA) status and neuroblastoma prognosis. We scre...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Yagyu, Shigeki, Iehara, Tomoko, Tanaka, Shiro, Gotoh, Takahiro, Misawa-Furihata, Akiko, Sugimoto, Tohru, London, Wendy B., Hogarty, Michael D., Teramukai, Satoshi, Nakagawara, Akira, Hiyama, Eiso, Maris, John M., Hosoi, Hajime
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981470/
https://ncbi.nlm.nih.gov/pubmed/27513929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161039
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