LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model

Persistent activation of the signal transducer and activator of transcription 3 (STAT3) signalling has been linked to oncogenesis and the development of chemotherapy resistance in glioblastoma and other cancers. Inhibition of the STAT3 pathway thus represents an attractive therapeutic approach for c...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Fuh, B, Sobo, M, Cen, L, Josiah, D, Hutzen, B, Cisek, K, Bhasin, D, Regan, N, Lin, L, Chan, C, Caldas, H, DeAngelis, S, Li, C, Li, P-K, Lin, J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
Fag:
Translational Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634692/
https://ncbi.nlm.nih.gov/pubmed/19127268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604793
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker