A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppressive Activity in Human Cancer Cells,

Constitutive activation of signal transducer and activator of transcription 3 (STAT3) signaling is frequently detected in cancer, promoting its emergence as a promising target for cancer treatment. Inhibiting constitutive STAT3 signaling represents a potential therapeutic approach. We used structure...

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Autors principals: Lin, Li, Hutzen, Brian, Li, Pui-Kai, Ball, Sarah, Zuo, Mingxin, DeAngelis, Stephanie, Foust, Elizabeth, Sobo, Matthew, Friedman, Lauren, Bhasin, Deepak, Cen, Ling, Li, Chenglong, Lin, Jiayuh
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press Inc. 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805882/
https://ncbi.nlm.nih.gov/pubmed/20072652
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