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Accumulation of Rhodopsin in Late Endosomes Triggers Photoreceptor Cell Degeneration
Progressive retinal degeneration is the underlying feature of many human retinal dystrophies. Previous work using Drosophila as a model system and analysis of specific mutations in human rhodopsin have uncovered a connection between rhodopsin endocytosis and retinal degeneration. In these mutants, r...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2633617/ https://ncbi.nlm.nih.gov/pubmed/19214218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000377 |
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